Disorder of Sexual Differentiation (DSD) – Expert Insights from Dr. Prabhu Karunakaran
Disorders of Sexual Differentiation (DSD) refer to a group of conditions where the development of chromosomal, gonadal, or anatomical sex is atypical. These conditions can present at birth or later in life and often require specialized medical evaluation and management.
Understanding DSD
DSD can result from various genetic, hormonal, or developmental factors affecting the formation of male or female characteristics. Early diagnosis and appropriate treatment are crucial for physical and psychological well-being.
Types of Disorders of Sexual Differentiation
- 46,XX DSD (Female Pseudohermaphroditism): Genetic females with male-like external genitalia due to excessive androgen exposure.
- 46,XY DSD (Male Pseudohermaphroditism): Genetic males with underdeveloped male genitalia due to inadequate testosterone or androgen receptor issues.
- Ovotesticular DSD: Presence of both ovarian and testicular tissue in an individual.
- Chromosomal DSD: Conditions such as Turner syndrome (45,X) or Klinefelter syndrome (47,XXY) leading to atypical sexual development.
Signs and Symptoms
- Atypical genitalia at birth
- Ambiguous external genitalia
- Delayed or absent puberty
- Differences in hormone levels affecting growth and development
- Infertility or menstrual irregularities
- Psychological concerns related to gender identity
When to Seek Medical Attention
Consult a pediatric urologist if your child shows:
- Unclear or ambiguous genitalia at birth
- Difficulty in determining sex at birth
- Delayed puberty or unusual physical development
- Unexpected hormonal changes during growth
Expert Care from a Pediatric Urologist
Dr. Prabhu Karunakaran, a specialized Pediatric Urologist in Hyderabad, provides expert evaluation and individualized treatment for children with DSD. His compassionate and multidisciplinary approach ensures both medical and psychological support for children and families.
Diagnostic & Treatment Approach
- Comprehensive medical history and genetic testing
- Hormonal evaluations and imaging studies
- Surgical options when necessary (genital reconstruction, gonadal management)
- Psychosocial support and gender identity counseling
- Long-term monitoring for growth, development, and reproductive health
Schedule a Consultation
Early diagnosis and intervention are crucial for managing DSD effectively. If you suspect any concerns regarding your child’s sexual differentiation, consult Dr. Prabhu Karunakaran for expert care and guidance.
